Dwayne Lee began his career at Yeading before spending time with Aldershot Town and then Exeter City whom he joined in 2003. He later played in a Conference-winning side at Barnet.

Yeading was pretty much Dwayne’s local club when he started playing adult football in 1998. After a short spell on loan at the higher-ranked Aldershot in late 2002, he eventually secured his move up the football ladder when he moved to the recently-relegated Exeter City in July 2003.

Dwayne made his debut against Stevenage Borough on 6 September 2003 scoring the only goal in a 1-0 win. He followed this up with two goals against Forest Green Rovers in his next game although oddly, in a season in which Dwayne played 24 times, these proved to be his only goals.

And, for a while, Dwayne’s arrival threatened to be City’s undoing as the Conference investigated whether there was an irregularity in Dwayne’s registration which - if found proven - could have led to a thirty-six point deduction.  The suspicion was eventually removed and Dwayne showed good enough form to be offered a new contract in addition to appearing twice for Grenada as a City player: first against Guyana in a World Cup qualifier on 14 March 2004; then in a friendly against Cuba on 20 May 2004.

However, Dwayne turned down the new contract and those three goals in his first two games proved to be the only ones of his Exeter career. Dwayne agreed terms with Barnet in August 2004 and played in 37 league games, scoring four times, as Barnet won the Conference in 2004/05. He then scored six league and cup goals during Barnet’s first season back in the Football League before moving back into non-league initially with Kidderminster Harriers, Stevenage Borough and Maidenhead United. Then, between 2008 and 2011, Dwayne played in turn for Kettering Town, Halesowen, AFC Wimbledon, Bromley, Boreham Wood, Windsor & Eton, Lewes and Staines Town. 

Eventually in October 2011 Dwayne returned to where he had started, signing for what was now Hayes and Yeading United. From there his playing career finished with Beaconsfield and Burnham before he later managed the under-23s at Hayes & Yeading and, briefly in 2019, London Tigers.