Edward Keeffe, who initially signed as an amateur from Exminster, appeared twice for Exeter City in the Football League in February 1935, He joined the police soon afterwards having already been awarded a medal for bravery when he saved a woman from drowning.

Predominantly a reserve team player, Edward joined Exeter City from Exminster as an amateur in 1931 and eventually signed professional forms in August 1934. He made his first-team debut against Gillingham on 16 February 1935 and retained his place for the following game against Reading. 

Not featuring for the first-team again, he quit professional football at the end of the season to join the police already having been awarded a Royal Humane Society certificate for saving a woman from drowning in the Exeter Canal in October 1934. It was reported that he was on his way to training at the time and that the woman was struggling violently.

Edward died in the Torbay area in 1990.